Search results for "Extended 5-yrs follow-up"

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Biodegradable collagen matrix implant versus mitomycin-C in trabeculectomy: five-year follow-up.

2015

Background Clinical studies comparing trabeculectomy augmented with Ologen implant (OLO) versus trabeculectomy plus mitomycin-C (MMC) show contradictory results. To obtain long-term data, we report an extended 5-year follow-up trial evaluating the safety and efficacy of OLO as adjuvant compared to low-dosage MMC in trabeculectomy. Methods Forty glaucoma patients (40 eyes) assigned to trabeculectomy with MMC or Ologen. Primary outcome: target IOP at ≤21, ≤17 and ≤15 mmHg; complete and qualified success endpoint rates. Secondary outcomes: visual acuity (VA), mean deviation (MD), bleb evaluation, according to Moorfields Bleb Grading System (MBGS); spectral domain OCT (SD-OCT) bleb examination;…

MaleIntraocular pressureVisual acuitygenetic structuresmedicine.medical_treatmentVisual AcuityGlaucomaExfoliation Syndrome0302 clinical medicineAbsorbable ImplantsTrabeculectomyExtended 5-yrs follow-upExtended 5-yrs follow-up; Mitomycin-C; Ologen; Trabeculectomy;GlycosaminoglycansGeneral MedicineMiddle AgedMitomycin-CFemaleCollagenmedicine.symptomGlaucoma Open-AngleTomography Optical CoherenceHumanResearch ArticleAdultmedicine.medical_specialtyAlkylating AgentsMitomycinTrabeculectomyOlogenFollow-Up Studie03 medical and health sciencesAbsorbable ImplantOphthalmologymedicineHumansIntraocular PressureAgedSettore MED/30 - Malattie Apparato Visivobusiness.industryMitomycin CFive year follow upANTIGLAUCOMA MEDICATIONSAlkylating Agentmedicine.diseaseeye diseasesSurgeryOphthalmologyGlycosaminoglycan030221 ophthalmology & optometryImplantsense organsbusiness030217 neurology & neurosurgeryFollow-Up StudiesBMC ophthalmology
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